A current study backs what experts in geriatrics have observed for years: having a purpose and keeping active as one ages can aid in diminishing cognitive decline.
For many years, professionals working with senior citizens have recognized a significant link: individuals who lead an active and involved lifestyle often enjoy better cognitive well-being. It has been established that remaining socially engaged, exercising regularly, and engaging in meaningful activities are crucial for maintaining brain health.
Now, we have concrete evidence.
Recently published findings offer the objective and scientific insights required to assure patients that lifestyle decisions can serve as effective preventive measures against cognitive decline and dementia.
This brings substantial hope for my colleagues and me. It means we can now offer patients and their families practical, research-supported guidance for addressing brain health as they age.
Recent findings bring hope
A key study, titled “Effects of Structured vs. Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The U. S. POINTER Randomized Clinical Trial,” was published in the Journal of the American Medical Association in July 2025.
At five clinics, 2,111 individuals at risk for cognitive decline participated, divided into two groups. Both groups were motivated to enhance their physical and cognitive activities, follow a nutritious diet, engage socially, and keep track of their heart health. One group received coaching assistance for these efforts, while the other was self-guided.
The results revealed that both groups experienced improvements in cognitive performance by adopting healthier lifestyles. However, the group that received structured coaching showed more significant advancements.
Another recent investigation, appearing in the American Journal of Geriatric Psychiatry in October 2025, explored the connection between life purpose and symptoms of depression. This study aimed to determine whether having a sense of purpose could lower the risk of or postpone the onset of cognitive impairment. It’s titled “Life Purpose Lowers Risk for Cognitive Impairment in a United States Population-Based Cohort. “
In this observational analysis, researchers reviewed data from 13,765 individuals participating in the Health and Retirement Study. All participants were over 45 years old and exhibited normal cognitive functioning.
After performing statistical evaluations that considered aspects such as race, gender, and genetics, findings indicated that those with a stronger sense of purpose in life had a 28% reduced likelihood of developing cognitive impairment compared to individuals with a weaker sense of purpose.
These results highlight that active participation is essential for preserving brain health as we age.
Related: Explore “Research Finds Caregiver Support Associated with Longer Survival in Homebound Older Adults. “
Defining cognitive decline and identifying those at risk
Social relationships: A mental workout.
During the COVID-19 pandemic, I served as a physician for older patients and witnessed how swiftly cognitive health can deteriorate, observing notable declines in memory and cognition, even among those who did not contract the virus.
The unifying element? Isolation.
Engaging in social activities is a vital form of mental exercise. Social interactions stimulate the brain in multiple ways:
